ALS The Neurodegenerative Trauma
![Image](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhMWR1u4rov-sRS48e9YWH1kIVixnJnMSsPztM5mHajRW1rWXEOoSY4NQM0-uPLKkHnsMZXgdOdtksY0dUFzUNf3no8R7uIsBWbErqCdSiryBFgB8tIUGh3s_sNWkVq5H3P26zmLnW0Rdns/s400/ALS-Treatment-Giostar2.jpg)
In the recent discovery of motor neuron diseases, scientists were able to convert cells isolated from skin, into neuronal cells without compromising their stemness . These promising findings are helpful in understanding some of the internal mechanism, that may have direct as well as indirect impact on ALS . So far, scientists could discover that stem cells play a major role in neuronal differentiation, which are being damaged in ALS . However, lot of questions still need to be answered regarding internal molecular pathways, that are forcing these differentiations to take place . Amyotrophic Lateral Sclerosis , or ALS is a deadly neurodegenerative condition, associated with massively damaged motor neurons . Due to this damage, signaling cascade providing information from central nervous system to muscles is being halted; leading to the neuromuscular damage . The pathophysiology of the disease is often associated with locomotary issues, progressive deterioration of involuntary