GIOSTAR REVIEWS

Osteoarthritis (OA) is the most common form of arthritis and it affects millions of people on the world. The disease brings about the ultimate destruction of synovial joints. For the patients, quality of life is reduced because of the loss of movement and function and, as the disease progresses, pain from the joint increase to become continuous, even occurring at rest. Underlying the disease is a loss of the normal homeostasis of the joint, generally leading to excessive catabolism relative to anabolism. The arthritic joint can, however, demonstrate apparent repair mechanism, although these often result in overactive but aberrant production of bone and cartilage in the form of osteophytes. OA was previously thought of as a wear and tear process. More recently it has been defined, not as a single condition, but rather a common complex disorder with three groups of risk factors: genetic, constitutional (aging and obesity) and local (biomechanical consequence of joint injury, joint laxi...

GIOSTAR Plans to Treat COVID-19 With Stem Cells

Diabetes is a type of devastating disorder, currently affecting millions of people around the world. The disease can primarily be categorized into type 1 as well as type 2 diabetes. The former one has primarily associated with the destruction of insulin-producing beta cells. The later form of diabetes, most commonly being identified to be as type 2-diabetes is generally characterized with the acquisition of insulin resistance; a condition is often associated with reduced secretion of insulin, further leading to the progressive decline in the functional attributes of beta cells. Accordingly, researchers are actively looking forward to developing a novel therapeutic solution that can be helpful in reducing the insulin dependency of the patients; if not completely at least the progression can be stopped to the great extent. However, there has been a very little awareness about how cell replacement therapy is important in producing enough number of beta cells and minimizing insul...