GIOSTAR REVIEWS

Stem cells have identified to be the mighty cells of multicellular organisms, with the ability to differentiate into multiple organs specific cells. They are the first cell to be found after the formation of zygote and are divided multiple times to give rise to an entire cellular system. The medical science has started exploiting this tremendous potential of stem cells to treat various diseases, which have so far, no cure through conventional medicine. Research has suggested that the loss of tissue specific cells is the fundamental issue for many degenerative disorders, such as Alzheimer’s disease, Parkinson’s disorder, arthritis , etc. Studies have evidently confirmed that many times, the damage is progressive, assuring no conventional treatment to fix the damage. However, stem cells being a natural component of our cellular system, have been proven as an excellent support system to make over the loss. So far, worldwide clinical studies have been completed to cater to t...

It will not be an exaggerated statement to declare that more than 3 million children are suffering with one of the several forms of arthritis, only in developed countries. As a matter of fact, amongst many identified forms, Juvenile Idiopathic Arthritis is the most common form, that is bothering children below 16 years of age. It is generally referred as the spontaneous exhibition of arthritic pain without any known or unknown cause. The Juvenile Idiopathic Arthritis is an autoimmune disorder, which triggers inflammation in synovial lining of affected joints. The exact antibodies that have been directed against the destruction of this synovial lining as a self are still a matter of debate, but the disorder has more obvious environmental linkups than genetic predisposition. Some of the common signs and symptoms of JIA can be featured as: ·          Sudden observation of red, inflamed and painful joints ·    ...

The therapeutic applications of stem cells in treating a variety of orthopedic conditions are relatively novel and exciting approach ! What are stem cells and are they useful is orthopedic stem cell therapy? Undifferentiated cells that are able to differentiate into specialized cell types are Stem cells. Stem cells come from blood, bone marrow, umbilical cord blood and adipose tissue. Orthopedic Stem-cell therapy is the use of stem cells to treat an injury or prevent an orthopedic disease or condition. These can be acute or chronic injuries of muscle, tendon, ligaments, bone deformities, cartilage like arthritis, rheumatoid arthritis or can be diseases like osteoporosis. What are all orthopedic conditions cured using Stem Cells? Various conditions and injuries can be treated using orthopedic stem cell therapy moreover; a lot of research investigations are being done worldwide to maximize the use of stem ce...

Congenital cerebral palsy , constitutes a number of locomotion and posture issues leading to nonprogressive disturbances in developing a fetus. In the past couple of decades, cerebral palsy is becoming the widest spread physical, developmental disability found to be prevalent in more than 2 live births out of 1000 children in developed countries. While investigating the underlying cause, researchers have decoded the link between maternal smoking and neuronal cell death that leads to the most common childhood physical disability. Studies have further indicated that when the brain is deprived of oxygen-rich blood for a longer period of time, it experiences an immediate oxidative stress and hypoxia ischemic injuries, causing neuronal cell death. Due to massive brain cell death, signaling pathways responsible for the passage of important information for regulating movement and memory retention are interrupted. In this regard, a new research published in the journal Fronti...

Many studies have reported that with the modern technology, it is now possible to treat massive diseases such as stroke with the help of patient’s own stem cells with more feasibility and safety. It has as well been reported that all the patients, who were involved in clinical studies very well tolerated the procedure with no complications, all the patients showed variable improvements, which was confirmed with the help of MRI and CT scan and lastly throughout the study, no signs of tumours or blood vessel malformation detected. Similar proof of concept trials has concluded complete safety and feasibility of stem cells treatment; as a possible alternative option in demand for many deadly conditions such as stroke. Till date, conditions such as stroke or paralysis were treated to be ultimate conditions; people have to stay with rest of their lives. But with the advent of stem cells technology, the scenario took a swift u turn towards a new path of hope and wellness. Many ongoing ...

Our lifestyle plays a very crucial role in maintaining one’s health. A liver is apparently a very important organ performing many different functions that are required to continue smooth functioning of our body mechanism. In order to maintain such a crucial organ in its functional state, it is thus utmost important to understand different good as well as bad lifestyle inventions, which influence smooth functioning of liver. Apparently, one should try to avoid parameters that are dangerous for liver and accept good habits, which can maintain it in a better form. Alcohol poisons and promotes inflammatory responses in the liver. If alcohol abuse continues, it can lead to permanent scarring of the liver (cirrhosis) . However, over three-fourths of the liver can be damaged before symptoms occur. If more than two alcoholic drinks are consumed each day, serious liver damage will eventually occur. The individual will tire more quickly since his blood is dirtier, and he will become more su...

Chronic liver disorder is being referred to as the largest cause of death in developed countries . It has been further evident that the said organ has its own regeneration capability due to native quota of stem cells, although the organ gets severely affected due to large insults like continuous alcoholism, steroidal hormonal exposure, consumption of high fat food, etc . In this regard, through conventional medicinal perspective the only available treatment is either liver transplant or long term consumption of anti-inflammatory medicines, which can add on the possibility of opportunistic infection. Thus, scientists were looking out for the better alternative therapeutic regimen that can stop the progression of damage and restore the function back; accordingly stem cells treatments have found to be very effective and viable option. Accordingly, a recently published report has suggested that patients with liver cirrhosis are at increased risk of stroke and that to haemorrhagic ...