Stem cells Treatment for Diabetes
Diabetes can be referred to as an autoimmune, metabolic disease that if
ignored for a longer period of time may lead to dangerous, debilitating effects
on body’s vital organs. Diabetes due to
its common prevalence can pose a very influential yet threatening burden on the
socioeconomic system of various developing nations. The disease is commonly
noted as a sugar disease as it mainly interferes with body’s sugar metabolism.
Our body derives energy from the food that is
being consumed by us, and is utilized for performing cellular functions. The
energy is retrieved in the form of sugar molecules that are transported from
blood to different cellular systems via hormone insulin, which is produced in
pancreas via beta cells. If in case, the body is not been able to produce
enough insulin or the insulin that is being produced is resistant to sugar
molecules then the sugar will remain in the blood, causing diabetes. The
disease is misleadingly mild in its initial level, but if ignored for a longer
period of time, it can give rise to deadly conditions, such as cardiovascular
disorders, critical limb ischemia, etc.; additionally, long term exposure to
high blood sugar level can damage many of the vital organs of the body like
kidney, heart, limb, etc. Thus, it is always advisable to manage the disease at
its initial level; rather than waiting it to be chronic, and hence one needs to
keep a check on the initial symptomatic expression of the disease. In this
regard, some of the common symptoms that have been reported are
- · Frequent thirst and an urge to urinate
- · Unusual fatigue
- · Unexplained weight loss
- · Unusually delayed healing of injury
- · Continuous sweet taste on tongue
- · Sudden numbness and/or needle like sensation in limbs
- · Blurry eyesight
According to the
abnormality in insulin function, diabetes can be broadly classified into two
major categories like Diabetes Type 1
& Diabetes Type 2. The former is associated with self destruction of
insulin producing pancreatic beta cells and the later is associated with inability
of insulin to carry sugar molecules. Conventionally, diabetes mellitus is
managed by certain prescribed steroidal drugs, diet and physical exercise;
however long term use of steroids can give rise to other complications and
hence should be avoided. Scientists worldwide were thus investigating
alternative treatment modality to regularize sugar metabolism and suppress immune
trauma to a great extent. In this regard, stem cells potential and their
applications in regenerative medicine have shown great potential.
Stem cells are the master cells of the body, which are observed to
differentiate into desired cell types, upon offering in vivo conditions. The
technology has thus enabled many medical professionals to manage complications
associated with dangerous diseases, such as diabetes. The richest reservoirs of
stem cells from our own body, like bone marrow and/or adipose tissues can be
extracted out of the body in a very controlled atmosphere and can be infused
back into the body via different route of administration. These cells are known
to migrate at the targeted site and regenerate lost cells to restore the
function back.
Thus, for the
diseases like diabetes, wherein it’s quite hard to completely cure the problem;
stem cells therapy can work wonders by potentially observing symptomatic
relief, reduce drug dependency and promote restoration of damaged function to
some extent.
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