Stem cells Treatments for Diabetes

In the developed countries, sedentary life styles, diet and other wrong adaptive habits can exact the toll of diabetes in millions of people; may be young as well as old. Over the period of time, research has unfolded many pages, which lead to better understanding of the mechanism but still the scarcity of effective treatment is troubling many medical practitioners. For decades now, researchers are making slow but steady development in the applications of stem cells treatment for diabetes.
Diabetes is basically categorized as the group of disorders that is deregulated by the body’s faulty immune system; leading to damaged insulin producing cells. This damage can alter the blood glucose metabolism, causing it to be accumulated in the blood. Due to long term exposure of this sweet blood to different functional organs, such as heart, kidney or vascular system; they can be damaged severely. Thus diabetes is a condition that can be asymptomatic in its initial phase but go bizarre in later part of its progression.

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Conventionally, no treatment is available for the condition, except for some supportive treatment approach such as hormonal supplements, diet control, regular exercise and weight loss. People have to follow their schedule strictly to manage the symptoms for their rest of the lives. It has been estimated that each year more than 1500, whole pancreatic transplant take place with more than 85% success rate. However, the demand for organs outweighs their availability. Besides, to allow the body to accept the transplanted organ, the patient has to be on strong supplementation, which may risk his life by other opportunistic infections.
Scientists have worked hard on developing a potential stem cell treatment diabetes. Since own cells are destroyed in autoimmune diseases such as type 1 diabetes; more emphasize would be in regulating immunological cells to deny their access of destruction. Stem cells are the potent cells with the ability to differentiate into different cells types depending upon the requirement. Modern technology has allowed easy isolation of these cells from different organs such as bone marrow, adipose tissue, etc. and infused back at the specific sites after laboratory enrichment. These cells then reprogram immune cells, reduce the initial inflammation and regenerate weakened cells to restructure cellular system of the pancreas to make it functionally powerful.
Thus, after addressing various safety and feasibility issues in various clinical studies, it has been clear that stem cells are undoubtedly promising candidates for implementing stem cells based therapies as routine practices for diseases such as diabetes.

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