ARTHRITIS WHAT YOU NEED TO KNOW MORE ABOUT?


Lifestyle changes have welcomed various health concerns like overweight, reduced bone density, infertility, etc.; which are indeed responsible for variety of underlying dangerous conditions such as arthritis. It has been estimated that around 50% people, over the age 65 can have arthritis. Hence, indeveloped countries, arthritis can be one of the leading health issues, which need to be tackled well within time to avoid increased social economic burden.

Arthritis can be categorized as an inflammatory, joint disorder; affecting multiple joints at a time. The condition has more than 100 subdivisions, with osteoarthritis and rheumatoid arthritis as the most common forms. It is simply known to be a slowly progressive disease, affecting persons of any age groups; although women are known to be more prevalent than men.


Our joints are made up of joining of two bones to allow easy movement. These joints are being protected with the underlying tissue named, cartilages. The cartilages are soft, spongy tissues; acting as beds in between the two bones. Due to the presences of these tissues, the friction between the two bones is reduced, while joints are in mobile state. The cartilages are as well supported with the presence of synovial fluid, which is helpful in shock absorption. Thus, the entire assembly can access an easy and long term functionality of joints. However, variety of issues such as obesity, smoking, poor diet, etc. can create non significant inflammatory responses, which can degenerate these supportive tissues such as cartilages and synovial fluid; exposing bones to outer shocks and friction, leading to their damage.

Stem cells are the young, privileged cells with the capacity to differentiate into cells of different origin. The property of stem cells can be uniquely identified to be potential treatment for arthritis patients. Autologous stem cells isolated from two different sources such as adipose tissue and/or bone marrow can provide mesenchymal and hematopoietic stem cells in abundance. These stem cells are enriched in the laboratory and infused back in the patient’s joints to avail maximum benefits of tissue function restoration. Once inside the body, these stem cells are known to reach at the site of injury, due to their strong communication pathways with other cells, secrete growth factors to reduce the inflammation and elicit strong immunological reactions to speed up the process of healing. Stem cells, in case of joints problems or arthritis are known to induce cells of Chondrocytes origin and get differentiated into cartilages. Once differentiated into cartilages, there can be reduced friction and pain associated with OA.

Thus, considering their anti-inflammatory and regenerative capacities; there are pretty good reasons to say that these stem cells can be good candidates for treatment.

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