GIOSTAR REVIEWS

Osteoarthritis (OA) is the most common form of arthritis and it affects millions of people on the world. The disease brings about the ultimate destruction of synovial joints. For the patients, quality of life is reduced because of the loss of movement and function and, as the disease progresses, pain from the joint increase to become continuous, even occurring at rest. Underlying the disease is a loss of the normal homeostasis of the joint, generally leading to excessive catabolism relative to anabolism. The arthritic joint can, however, demonstrate apparent repair mechanism, although these often result in overactive but aberrant production of bone and cartilage in the form of osteophytes. OA was previously thought of as a wear and tear process. More recently it has been defined, not as a single condition, but rather a common complex disorder with three groups of risk factors: genetic, constitutional (aging and obesity) and local (biomechanical consequence of joint injury, joint laxi...

GIOSTAR Plans to Treat COVID-19 With Stem Cells

Diabetes is a type of devastating disorder, currently affecting millions of people around the world. The disease can primarily be categorized into type 1 as well as type 2 diabetes. The former one has primarily associated with the destruction of insulin-producing beta cells. The later form of diabetes, most commonly being identified to be as type 2-diabetes is generally characterized with the acquisition of insulin resistance; a condition is often associated with reduced secretion of insulin, further leading to the progressive decline in the functional attributes of beta cells. Accordingly, researchers are actively looking forward to developing a novel therapeutic solution that can be helpful in reducing the insulin dependency of the patients; if not completely at least the progression can be stopped to the great extent. However, there has been a very little awareness about how cell replacement therapy is important in producing enough number of beta cells and minimizing insul...

Osteoarthritis routinely abbreviated as OA, is a common joint disorder mostly affecting middle age or elderly people. Classically, the condition was thought to be due to overuse or high pressured joints, but it has recently to be understood as the abnormality, associated with the entire joints, involving different parts such as cartilages, joint lining, ligaments and bones. The condition primarily symbolizes the breakdown of the cartilages; the tissue that is padded between the two bones for the ease of movement and lubrication. It as well specifies the deterioration of tendons, ligaments and various degree of inflammation of the joint-lining also called as synovium.   The OA is mainly prevalent for knee joints although it can be widespread to any joints of the body such as joints of hands, spine, hips and toes. However, life time risk of development of osteoarthritis is about 46% for knees, due to their weight bearing nature. Knowing your condition about Osteoarthritis ...

Currently, healthcare system is facing variety of challenges globally; finding an effective diabetes treatment is one of them. Diabetes is the Simplest version of the metabolic diseases with very remote risk factors; which are yet to be pinpointed. The symptoms of this mysterious disease can be controlled but cannot be cured completely. However, the promises made by science of regenerative medicines and stem cells, have given a new hope to the medical fraternity.             Stem cells are the unique precursor cells of the body, with the great potential to differentiate into variety of cells, on demand. This property of stem cells can as well be applied to the diseases like diabetes, wherein human body is in crisis of insulin producing beta cells; more commonly known as the pancreatic cells. This facet of regenerative medicine has sparked great interest in many scientists in order to achieve a hallmark therapy for diabetes with th...

San Diego, California-based Global Institute of Stem Cell Therapy and Research, a leader in stem cell research, has announced that they have received an approval for a COVID-19 clinical trial, led by their Indian American medical director Dr. Prabhat Soni. GIOSTAR will conduct the trial using stem cells to treat COVID-19 patients under the approval of the United States Food and Drug Administration “expanded access for compassionate use” program, said a PRNewswire report. The institute is exploring a promising alternative approach to the devastating disorder, which leverages the anti-inflammatory properties of mesenchymal stem cells (MSCs). According to Soni, the investigation is based upon two decades of stem cell research by GIOSTAR’s Indian American co-founder, chairman and chief scientific officer Dr. Anand Srivastava. The COVID-19 pandemic has resulted in unprecedented disruption, with more than 3 million cases and 200,000 deaths reported worldwide as of May 1, 2020, a f...

Lifestyle changes have welcomed various health concerns like overweight, reduced bone density, infertility, etc.; which are indeed responsible for variety of underlying dangerous conditions such as arthritis. It has been estimated that around 50% people, over the age 65 can have arthritis. Hence, indeveloped countries, arthritis can be one of the leading health issues, which need to be tackled well within time to avoid increased social economic burden. Arthritis can be categorized as an inflammatory, joint disorder; affecting multiple joints at a time. The condition has more than 100 subdivisions, with osteoarthritis and rheumatoid arthritis as the most common forms. It is simply known to be a slowly progressive disease, affecting persons of any age groups; although women are known to be more prevalent than men. Our joints are made up of joining of two bones to allow easy movement. These joints are being protected with the underlying tissue named, cartilages. The cartil...