New Avenue Of Stem Cells For Liver Cirrhosis Treatment
Cirrhosis occurs when
regenerative nodules encircled with fibrous bands develops because of acute
liver injury, and this leads to liver disease of the last stage. With recent
developments in medical science Pathophysiology and history of cirrhosis is now
better understood leading to improved management of the disease as well as
improved life expectancy.
Until now, liver transplant was
the only cure available for Liver Cirrhosis Treatment, but Stem Cell
Therapy has opened up new borders for patients suffering from such fatal
disease. In many conditions related to the liver, stem cells have proven
beneficial and research also proves that in the time to come Stem Cell Therapy
can emerge as a complete cure for liver diseases, like many other degenerative
diseases.
Researchers are working on every
possibility of using Stem Cell Therapy
for Liver Cirrhosis Treatment and replace the option of liver
transplant. For this they have studied different cell types including embryonic
cells, mesenchymal cells, and even pluripotent cells.
The reason why many prefer
embryonic cells for Liver Cirrhosis Treatment is because they can be
extracted from varied sources like umbilical cord, bone marrow, etc. and these
cells has the ability of going through different cell division cycles but can
still maintain its undifferentiated state. However, ethical issues pose a
restriction for this kind of Stem Cell Therapy.
Another promising advancement in Stem
Cell Therapy is the discovery of induced pluripotent cells. With modern
scientific techniques scientists can now produce these cells in huge numbers
and can transplant them in the affected organ where they can help in
regeneration of the organ.
These cells are normally
extracted from human skin as well as blood and then these are converted to
their original state before being injected into the liver. The advantage of these
cells is that they are available in plenty and they multiply easily in lab
conditions. Another benefit of these cells is that they can be customized
according to the needs of a patient and so there is lesser risk of immune
rejection, which is common in transplants for liver cirrhosis.
Researchers are also studying
different techniques of using liver cells for treating patients. Several
studies that use mesenchymal cells from bone marrow have been done, as these
cells can differentiate in many other cell types.
Apart from these trials and
tests, researchers are also testing methods that can work in the long term for Liver Cirrhosis Treatment.
They are trying to formulate drugs, which can be introduced in a patient and
then can be targeted in a way that it can repair the damaged tissues of the
liver. However, many other trials are yet to be done on this kind of
regenerative medicine for treatment of similar disorders.
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