Stem cells Treatment for Liver Cirrhosis
Chronic liver disorder is being referred to
as the largest cause of death in developed countries. It has been further evident that
the said organ has its own regeneration capability due to native quota of stem cells,
although the organ gets severely affected due to large insults like continuous
alcoholism, steroidal hormonal exposure, consumption of high fat food, etc. In this regard, through
conventional medicinal perspective the only available treatment is either liver
transplant or long term consumption of
anti-inflammatory medicines, which can add on the possibility of opportunistic
infection. Thus, scientists were looking out for the better alternative
therapeutic regimen that can stop the progression of damage and restore the
function back; accordingly stem cells treatments have found to be very
effective and viable option.
Accordingly, a recently published report has suggested that patients with
liver cirrhosis are at increased risk of stroke and that to haemorrhagic stroke. In
fact, it has been referred to as a leading cause of death and/or the
disability. However, swift treatments can ultimately make a difference to the
extent that death will be diverted to survival with a disability. As a matter
of fact, people with higher inclination towards fatty liver should positively
understand the warning signs of stroke to reduce its aftereffects.
About Liver
cirrhosis
Experts have recommended that liver cirrhosis affecting, more that
quarter of the people, living in developed countries. Liver is a very crucial
organ, involved in the metabolism of nutrients and removal of toxins outside
the body. It is involved in the filtration process to get rid of toxic
substances, drugs, etc. and as well maintains the level of blood sugar, fat and
hormones, while participating in different types of immunological responses.
The liver is as well being identified as the largest organ and the
biggest reservoir of blood in the human body. It is equipped with its own quota
of resident stem cells, which are responsible for normal wear and tear of the
liver. Although, disease conditions, such as liver cirrhosis are progressively
damaging, causing severe cellular loss that can be made up only with the help
of liver transplantation, in the later stage of the disease.
For that matter, science and technology has come up with the option of
autologous and allogenic stem cells treatments; which have been found to be
very effective.
Stem cells are the basic cells of the body, with the ability to
differentiate into different types of cells through the passage of proper of
signalling network. The technology has recently enabled isolation of stem cells
from autologous sources, such as adipose tissues as well as bone marrow, under
controlled condition and are infused back, directly at the site of infusion. It
is being researched, once infused back in the body, this enriched fraction of
active stem cells can differentiate into hepatocytes and other important cells
that are being lost during progressive liver cirrhosis.
Thus, although a road towards a definitive cure in liver cirrhosis with
the help of stem cells has been opened up, it still has many blocks to
overcome; although, currently stem cells therapy for liver cirrhosis is the
only viable alternative found to be effective in its functional restoration,
reduction in inflammatory responses and reduced progression without the need
for surgery and transplantation.
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