GIOSTAR REVIEWS

Through the recent publication, it has been quite evident that just by enhancing one’s breathing capacity; it is possible to limit breathing capacity of the person, suffering with DMD. Duchenne Muscular Dystrophy is a genetic disorder with neuromuscular degeneration; in the later stage, the disorder may lead to gradual depletion of a respiratory power. The said, respiratory muscular dysfunction is a characterized assessment of DMD. The estimated prevalence rate of muscular dystrophies is almost 1 in 7000 male children between the age 5 to 24 years. It has been surveyed to be rapidly progressing neuromuscular, congenital disorder that is exclusively observed in male children. The disorder is typically characterized with muscular weakness, leading to the increased disability. There are various types of muscular dystrophies, which have variable degree of severity, age of onset and life expectancy. Initial symptoms reported in patients with DMD are delayed walking, frequent f...

In the recent discovery of motor neuron diseases, scientists were able to convert cells isolated from skin, into neuronal cells without compromising their stamens. These promising findings are helpful in understanding some of the internal mechanism, that may have direct as well as indirect impact on ALS. So far, scientists could discover that stem cells play a major role in neuronal differentiation, which are being damaged in  ALS . However, lot of questions still need to be answered regarding internal molecular pathways, that are forcing these differentiations to take place. Amyotrophic Lateral Sclerosis, or ALS is a deadly neurodegenerative condition, associated with massively damaged motor neurons. Due to this damage, signaling cascade providing information from central nervous system to muscles is being halted; leading to the neuromuscular damage. The pathophysiology of the disease is often associated with locomotary issues, progressive deterioration of involuntary as wel...

Stem cells therapy has been acknowledged to be a new medical boon, and many of us want to hear about the latest advancements and discoveries in stem cells and the science of regenerative medicine. Myriad of degenerative conditions have been harassing the mankind, mainly due to unavailability of concrete treatment pattern in the conventional way of medicine. For that matter, scientists all over the world are trying to explore inherent mechanism that is forcing stem cells to repair and regenerate. Stem cells are identified to be the naïve cells of our body, which are involved in defining the entire cellular system. Although, stem cells applications have been recently explored, since the year 1970’s blood stem cells are widely used to treat many blood related disorders, like leukemia, malignant diseases, etc. The treatment can now be categorized as approved therapy and is being beneficial to many patients, who have been suffering with variety of blood related disorders. Further ...

The World Health Organization has recorded a global data of 36 million people, who have been suffering with type 1 diabetes ; which definitely raise an alarming situation. Diabetes is an autoimmune disorder, wherein body’s own immune cells attack and destroy insulin producing islets cells, due to which, glucose metabolism is affected. This, in deed requires stringent monitoring of sugar level and lifelong dependency on external insulin administration. While so far, no successful treatment has been reported conventionally to completely cure the issue, stem cells transplantation has reported to show successful outcome in many clinical investigations. Further to which, diabetes if ignored for a longer period of time can give rise to multiple organ failure, due to constant exposure to the higher blood glucose. Stem cells are the naïve cells of human body, with the ability to differentiate into multiple cells types; upon passage through the cascade of signalling pathways. These cells ...

Millions of people suffer from arthritis, but even after being such a common condition very less is known about the root cause of arthritis. This condition, in fact, is not a single ailment, but a number of joint diseases and pain together are referred to as arthritis. There are different types of this condition that affects people around the world, and it is growing to become one of the primary causes of disability as well. Arthritis Treatment involves preserving functioning of the joint, and improving mobility at the same time. Drugs are given to control inflammation and pain, but there is no complete Arthritis Treatment option. With evolution of Stem Cell Therapy , it has proved beneficial even for Arthritis Treatment . Researchers are studying the viability of using stem cells to treat main types of this disease, which are osteoarthritis and rheumatoid arthritis. The first one is a degenerative condition, which involve degradation of subchondral bone and articular cartilage...

The World Health Organization has recorded a global data of 36 million people, who have been suffering with type 1 diabetes ; which definitely raise an alarming situation. Diabetes is an autoimmune disorder, wherein body’s own immune cells attack and destroy insulin producing islets cells, due to which, glucose metabolism is affected. This, in deed requires stringent monitoring of sugar level and lifelong dependency on external insulin administration. While so far, no successful treatment has been reported conventionally to completely cure the issue, stem cells transplantation has reported to show successful outcome in many clinical investigations. Further to which, diabetes if ignored for a longer period of time can give rise to multiple organ failure, due to constant exposure to the higher blood glucose. Stem cells are the naïve cells of human body, with the ability to differentiate into multiple cells types; upon passage through the cascade of signalling pathways. These cells ...

Diabetes is an autoimmune metabolic disorder, generally characterized by high blood sugar level in the blood or lack of insulin to metabolize sugar. It is certainly not a deadly disease but is typically a chronic disease with reduced life expectancy due to other complications such as diabetic foot, organ damage, cardiovascular complications, blindness, etc. The disease is rightly called as silent killer, as the condition goes asymptomatic for years. Although, certain life style changes have been observed such as increased thirst, frequent urination and/ or improved appetites. What causes diabetes is a matter of debate; as various studies have put forth different risk factors. Some of the preliminary causative factors for the disease can be obesity, poor diet and lack of activity as well as genetic makeup of the individual. Apart from the factors mentioned above, others are old age, high blood pressure, ethnicity, etc. It is very important to know, what is happening inside your b...